AKT2 Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ChIP, ICC, IF, IHC, IP, WB |
Recommended Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:100 ICC,1:50 - 1:200 IF,1:50 - 1:100 IP,1:20 - 1:50 ChIP,1:20 - 1:100 |
Reactivities | Human, Monkey, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human AKT2 |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 51kDa/55kDa |
Gene Name | AKT serine/threonine kinase 2 |
Database Link | |
Background | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
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