TCP1 beta (CCT2) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IP, WB |
Recommended Dilution | WB,1:500 - 1:2000 IF,1:50 - 1:200 IP,1:50 - 1:100 |
Reactivities | Human, Mouse |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 206-535 of human TCP1 beta/TCP1 beta/CCT2 (NP_006422.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 52kDa/57kDa |
Gene Name | chaperonin containing TCP1 subunit 2 |
Database Link | |
Background | The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. |
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