Cgas Rabbit Polyclonal Antibody

CAT#: TA374688

Phospho-CGAS-S291 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

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Other products for "CGAS"

Specifications

Product Data
Applications WB
Recommended Dilution WB,1:500 - 1:2000
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A phospho synthetic peptide corresponding to residues surrounding S291 of Mouse CGAS.
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Gene Name cyclic GMP-AMP synthase
Background The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.