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CUEDC2 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | WB |
| Recommended Dilution | WB,1:500 - 1:2000 |
| Reactivities | Rat |
| Modifications | Unmodified |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CUEDC2 (NP_076945.2). |
| Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Stability | Shelf life: one year from despatch. |
| Predicted Protein Size | 32kDa |
| Gene Name | CUE domain containing 2 |
| Database Link | |
| Background | Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. |
| Reference Data | |
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