MCK10 (DDR1) Rabbit Polyclonal Antibody

CAT#: TA375378

Phospho-DDR1-Y792 Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using Phospho-DDR1-Y792 antibody (TA375378) at 1:1000 dilution. 293T cells were treated by ATP(5 mM) at 30℃ for 1 hour. NIH/3T3 cells were treated by ATP(5 mM) at 30℃ for 1 hour. C6 cells were treated by ATP(5 mM) at 30℃ for 1 hour. |Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% BSA.|Detection: ECL Basic Kit .|Exposure time: 1s.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB,1:500 - 1:2000
  ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
• Reactivities: Human, Mouse, Rat
• Modifications: Phospho Y792
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Formulation: Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 101kDa
• Gene Name: discoidin domain receptor tyrosine kinase 1
• Database Link:
  Entrez Gene 780 Human
  UniProt ID Q08345
• Background: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Synonyms: CAK; CD167; DDR; EDDR1; HGK2; MCK-10; MCK10; NEP; NTRK4; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; PTK3; PTK3A; RTK6; TRKE