XPF (ERCC4) Rabbit Polyclonal Antibody
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Other products for "ERCC4"
Specifications
Product Data | |
Applications | IP, WB |
Recommended Dilution | WB,1:500 - 1:2000 IP,1:20 - 1:50 |
Reactivities | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human ERCC4 (NP_005227.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 42kDa/104kDa |
Gene Name | ERCC excision repair 4, endonuclease catalytic subunit |
Database Link | |
Background | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
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