GBA Rabbit Polyclonal Antibody

CAT#: TA376498

Glucosylceramidase beta (GBA) Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of various cell lines, using Glucosylceramidase beta (Glucosylceramidase beta (GBA)) Rabbit pAb (TA376498) at 1:1000 dilution.|Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25ug per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Basic Kit .|Exposure time: 10s.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:2000
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 29kDa/50kDa/54kDa/57kDa/59kDa
• Gene Name: glucosylceramidase beta
• Database Link:
  Entrez Gene 2629 Human
  UniProt ID P04062
• Background: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
• Synonyms: Alglucerase; beta-glucocerebrosidase; GBA1; GC; GCB; GLUC; glucocerebrosidase; Imiglucerase