NMDAR1 (GRIN1) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB,1:500 - 1:2000 |
Reactivities | Human, Rat |
Modifications | Phospho S890 |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A phospho specific peptide corresponding to residues surrounding S890 of human NMDAR1 |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 99kDa/101kDa/103kDa/105kDa/106kDa/107kDa |
Gene Name | glutamate ionotropic receptor NMDA type subunit 1 |
Database Link | |
Background | The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. |
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