HIST2H2BE Rabbit Polyclonal Antibody

CAT#: TA377050

Acetyl-Histone H2B-K12 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: ChIP, IF, IHC, WB
• Recommended Dilution: WB,1:500 - 1:2000
  IHC,1:50 - 1:200
  IF,1:50 - 1:200
  ChIP,1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Acetyl K12
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 13kDa
• Gene Name: histone cluster 2 H2B family member e
• Database Link:
  Entrez Gene 8349 Human
  UniProt ID Q16778
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.