H3FJ (HIST1H3J) Rabbit Polyclonal Antibody

CAT#: TA377067

Acetyl-Histone H3-K18 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: ChIP, IF, IHC, IP, WB
• Recommended Dilution: WB,1:1000 - 1:3000
  IHC,1:200 - 1:500
  IF,1:500 - 1:1000
  IP,1:200 - 1:500
  ChIP,1:50 - 1:100
  ChIP-seq,1:50 - 1:100
• Reactivities: Human, Mouse, Rat
• Modifications: Acetyl K18
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic acetylated peptide corresponding to residues surrounding K18 of human H3
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 15kDa
• Gene Name: histone cluster 1 H3 family member j
• Database Link:
  Entrez Gene 8356 Human
  UniProt ID P68431
• Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.