IGF1 Receptor (IGF1R) Rabbit Polyclonal Antibody

CAT#: TA377374

Phospho-INSR-Y1189/Y1190 + IGF1R-Y1165/Y1166 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

Product Images

Other products for "IGF1R"

Specifications

Product Data
Applications WB
Recommended Dilution WB,1:500 - 1:2000
Reactivities Human, Mouse, Rat
Modifications Phospho Y1189/Y1190,Phospho Y1165/Y1166
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A phospho specific peptide corresponding to residues surrounding Y1189/Y1190 of human INSR and Y1165/Y1166 of human IGF1R.
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 154kDa/155kDa/156kDa
Gene Name insulin like growth factor 1 receptor
Background This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.