KDM4A Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC, IP, WB |
Recommended Dilution | WB,1:500 - 1:2000 IHC,1:50 - 1:200 IP,1:50 - 1:100 |
Reactivities | Human, Mouse |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 585-815 of human KDM4A (NP_055478.2). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 54kDa/120kDa |
Gene Name | lysine demethylase 4A |
Database Link | |
Background | This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
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