KDM5A Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | ChIP, IP, WB |
Recommended Dilution | WB,1:500 - 1:2000 IP,1:50 - 1:200 ChIP,1:50 - 1:200 |
Reactivities | Human, Rat |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human KDM5A |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 186kDa/192kDa |
Gene Name | lysine demethylase 5A |
Database Link | |
Background | This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression. |
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