LAT Rabbit Polyclonal Antibody

CAT#: TA377962

Phospho-LAT-Y191 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution WB,1:500 - 1:2000
Reactivities Human, Mouse
Modifications Phospho Y191
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A phospho specific peptide corresponding to residues surrounding Y191 of human LAT
Formulation Buffer: PBS with 0.02% sodium azide,1% BSA,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 24kDa/27kDa/28kDa
Gene Name linker for activation of T cells
Background The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.