PLCG 2 (PLCG2) Rabbit Polyclonal Antibody

CAT#: TA380021

Phospho-PLC gamma 2 (PLCG2)-Y1217 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:200
Reactivities Human, Mouse
Modifications Phospho Y1217
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic phosphorylated peptide around Y1217 of human PLC gamma 2 (PLCG2) (NP_002652.2).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 147kDa
Gene Name phospholipase C gamma 2
Background The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.