CD133 (PROM1) Rabbit Polyclonal Antibody

CAT#: TA380398

CD133 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: WB,1:1000 - 1:3000
  IF,1:50 - 1:200
  IP,1:50 - 1:200
• Reactivities: Human, Mouse, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 750-850 of human CD133 (NP_006008.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 92kDa/93kDa/94kDa/96kDa/97kDa
• Gene Name: prominin 1
• Database Link:
  Entrez Gene 8842 Human
  UniProt ID O43490
• Background: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.