PTP alpha (PTPRA) Rabbit Polyclonal Antibody

CAT#: TA380541

Phospho-PTPRA-Y789 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications WB
Recommended Dilution WB,1:500 - 1:2000
Reactivities Human, Mouse, Rat
Modifications Phospho Y789
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A phospho specific peptide corresponding to residues surrounding Y789 of human PTPRA
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 89kDa/90kDa
Gene Name protein tyrosine phosphatase receptor type A
Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.