Pregnancy zone protein (PZP) Rabbit Polyclonal Antibody

CAT#: TA380594

PZP Rabbit polyclonal Antibody


USD 220.00

3 Weeks*

Size
    • 100 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution WB,1:500 - 1:2000
Reactivities Human, Mouse, Rat
Modifications Unmodified
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 620-740 of human PZP (NP_002855.2).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 140kDa/163kDa
Gene Name PZP alpha-2-macroglobulin like
Background The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.