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QPRT Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | WB |
| Recommended Dilution | WB,1:500 - 1:2000 |
| Reactivities | Human, Mouse, Rat |
| Modifications | Unmodified |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human QPRT (NP_055113.2). |
| Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Stability | Shelf life: one year from despatch. |
| Predicted Protein Size | 30kDa |
| Gene Name | quinolinate phosphoribosyltransferase |
| Database Link | |
| Background | This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.