RAB7 (RAB7A) Rabbit Polyclonal Antibody

CAT#: TA380646

RAB7 Rabbit polyclonal Antibody


USD 220.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution WB,1:500 - 1:2000
IHC,1:10 - 1:100
Reactivities Human, Mouse, Rat
Modifications Unmodified
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RAB7 (NP_004628.4).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 23kDa
Gene Name RAB7A, member RAS oncogene family
Background RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.