RbAp46 (RBBP7) Rabbit Polyclonal Antibody

CAT#: TA380756

RBBP7 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: ChIP, IF, WB
• Recommended Dilution: WB,1:500 - 1:2000
  IF,1:50 - 1:200
  ChIP,1:50 - 1:200
• Reactivities: Human, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human RBBP7 (NP_002884.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 47kDa/52kDa
• Gene Name: RB binding protein 7, chromatin remodeling factor
• Database Link:
  Entrez Gene 5931 Human
  UniProt ID Q16576
• Background: This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.