MSK2 / RSK-B (RPS6KA4) Rabbit Polyclonal Antibody

CAT#: TA381127

RPS6KA4 Rabbit polyclonal Antibody

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB,1:200 - 1:1000
  IHC,1:20 - 1:100
  IF,1:20 - 1:100
• Reactivities: Human, Mouse, Rat
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human RPS6KA4 (NP_003933.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 84kDa/85kDa
• Gene Name: ribosomal protein S6 kinase A4
• Database Link:
  Entrez Gene 8986 Human
  UniProt ID O75676
• Background: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for this gene.