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SnoN (SKIL) Rabbit Polyclonal Antibody
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Other products for "SKIL"
Specifications
| Product Data | |
| Applications | WB |
| Recommended Dilution | WB,1:500 - 1:2000 |
| Reactivities | Human, Mouse, Rat |
| Modifications | Unmodified |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 420-684 of human SKIL (NP_001234937.1). |
| Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Stability | Shelf life: one year from despatch. |
| Predicted Protein Size | 44kDa/46kDa/71kDa/74kDa/76kDa |
| Gene Name | SKI like proto-oncogene |
| Database Link | |
| Background | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.