STAT1 Rabbit Polyclonal Antibody

CAT#: TA382088

Phospho-STAT1-S727 Rabbit polyclonal Antibody


USD 300.00

3 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Applications IHC, IP, WB
Recommended Dilution WB,1:500 - 1:2000
IHC,1:50 - 1:100
IP,1:50 - 1:100
Reactivities Human, Mouse, Rat
Modifications Phospho S727
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic phosphorylated peptide around S727 of human STAT1 (NP_009330.1).
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Stability Shelf life: one year from despatch.
Predicted Protein Size 83kDa/87kDa
Gene Name signal transducer and activator of transcription 1
Background The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.