Tyrosine Hydroxylase (TH) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB,1:500 - 1:2000 |
Reactivities | Rat |
Modifications | Phospho S40 |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A phospho specific peptide corresponding to residues surrounding S40 of human Tyrosine Hydroxylase. |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 44kDa/45kDa/55kDa/56kDa/58kDa |
Gene Name | tyrosine hydroxylase |
Database Link | |
Background | The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008] |
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