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UPB1 Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | WB |
| Recommended Dilution | WB,1:200 - 1:2000 |
| Reactivities | Mouse, Rat |
| Modifications | Unmodified |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human UPB1 (NP_057411.1). |
| Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Stability | Shelf life: one year from despatch. |
| Predicted Protein Size | 43kDa |
| Gene Name | beta-ureidopropionase 1 |
| Database Link | |
| Background | This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.