WWOX Rabbit Polyclonal Antibody
Other products for "WWOX"
Specifications
Product Data | |
Applications | ICC/IF, WB |
Recommended Dilution | WB,1:1000 - 1:2000 IF,1:50 - 1:200 |
Reactivities | Human, Mouse, Rat |
Modifications | Unmodified |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human WWOX (NP_057457.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20℃. Avoid freeze / thaw cycles. |
Stability | Shelf life: one year from despatch. |
Predicted Protein Size | 4kDa/21kDa/23kDa/26kDa/35kDa/41kDa/46kDa |
Gene Name | WW domain containing oxidoreductase |
Database Link | |
Background | This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants. |
Synonyms | D16S432E; FOR; FRA16D; HHCMA56; PRO0128; SDR41C1; WOX1 |
Reference Data |
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