WWP2 Rabbit Polyclonal Antibody

CAT#: TA383361

WWP2 Rabbit polyclonal Antibody

Product Images

Western blot analysis of extracts of A-549 cells, using WWP2 antibody (TA383361).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB,1:500 - 1:2000
• Reactivities: Human
• Modifications: Unmodified
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 151-400 of human WWP2 (NP_001257383.1).
• Formulation: Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
• Concentration: lot specific
• Purification: Affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20℃. Avoid freeze / thaw cycles.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: 35kDa/51kDa/86kDa/98kDa
• Gene Name: WW domain containing E3 ubiquitin protein ligase 2
• Database Link:
  Entrez Gene 11060 Human
  UniProt ID O00308
• Background: This gene encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.
• Synonyms: AIP2; OTTHUMP00000174895; WWp2-like