ATP citrate lyase (ACLY) Rabbit Polyclonal Antibody

CAT#: TA383654

ATP Citrate lyase Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human brain carcinoma, using ATP citrate lyase Antibody .

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  Western blot analysis of ATP citrate lyase expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human ATP citrate lyase
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 122kDa
• Gene Name: ATP citrate lyase
• Database Link:
  Entrez Gene 47 Human
  UniProt ID P53396
• Background: Swiss-Prot Acc.P53396.ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
• Synonyms: ACL; ATPCL; CLATP; OTTHUMP00000164773