ADCY5 Rabbit Polyclonal Antibody

CAT#: TA383678

ADCY5/6 Rabbit polyclonal Antibody

Product Images

Western blot analysis of ADCY5/6 in various lysates using ADCY5/6 antibody.

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  Western blot analysis of ADCY5/6 in COLO205 lysates using A Cyclase V/VI antibody.

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  Western blot analysis of ADCY5/6 in COLO25 lysates using ADCY5/6 antibody. The lane on the right is blocked with the synthesized peptide.

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  Western blot analysis of ADCY5/6 in HUVEC lysates using ADCY5/6 antibody.

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/100-1/300
  IF: 1/200-1/1000
  ELISA: 1/10000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):138
• Gene Name: adenylate cyclase 5
• Database Link:
  Entrez Gene 111 Human
  UniProt ID O95622
• Background: Swiss-Prot Acc.O95622/O43306.ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.
• Synonyms: AC5