Ataxin 1 (ATXN1) Rabbit Monoclonal Antibody [Clone ID: R01-8H1]

CAT#: TA383788

Ataxin 1 Rabbit monoclonal Antibody

Specifications

Product Data

• Clone Name: R01-8H1
• Applications: IP, WB
• Recommended Dilution: WB: 1/1000
  IP: 1/20
• Reactivities: Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human Ataxin 1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 87 kDa; Observed MW: 105 kDa
• Gene Name: ataxin 1
• Database Link:
  UniProt ID P54253
• Background: Swiss-Prot Acc.P54253.Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development .
• Synonyms: ATX1; D6S504E; OTTHUMP00000016065; SCA1