Aurora B (AURKB) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IHC, IP, WB |
Recommended Dilution | WB: 1/1000-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human Aurora B |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 39kDa |
Gene Name | aurora kinase B |
Database Link | |
Background | Swiss-Prot Acc.Q96GD4.May be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. |
Synonyms | AIK2; AIM-1; AIM1; ARK2; AurB; aurkb-sv1; aurkb-sv2; aurora-1; aurora-B; IPL1; STK-1; STK5; STK12 |
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