beta 2 Microglobulin (B2M) Rabbit Monoclonal Antibody [Clone ID: R01-4H5]

CAT#: TA383794

beta 2 Microglobulin Rabbit monoclonal Antibody

Specifications

Product Data

• Clone Name: R01-4H5
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/200
  IP: 1/20
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human beta 2 Microglobulin
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 14 kDa; Observed MW: 14 kDa
• Gene Name: beta-2-microglobulin
• Database Link:
  Entrez Gene 567 Human
  UniProt ID P61769
• Background: Swiss-Prot Acc.P61769.Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
• Synonyms: beta-2-microglobin; beta-2-microglobulin