BAD Rabbit Monoclonal Antibody [Clone ID: R07-1B6]

CAT#: TA383799

Bad Rabbit monoclonal Antibody

Product Images

Western blot analysis of Bad in rat Brain, C6, 3T3, Hela lysates using Bad antibody.

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  Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Bad antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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  Immunocytochemistry analysis of Bad(green) in Hela using Bad antibody,and DAPI(blue)

Specifications

Product Data

• Clone Name: R07-1B6
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50
  ICC/IF: 1/50
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Bad
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 18 kDa; Observed MW: 23 kDa
• Gene Name: BCL2 associated agonist of cell death
• Database Link:
  Entrez Gene 572 Human
  UniProt ID Q92934
• Background: Swiss-Prot Acc.Q92934.Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
• Synonyms: BBC2; BBC6; Bcl2-L-8; BCL2L8