Caldesmon (CALD1) Rabbit Monoclonal Antibody [Clone ID: R05-3D2]

CAT#: TA383854

Caldesmon Rabbit monoclonal Antibody

Product Images

Western blot detection of CALD1 in C6,3T3,Hela cell lysates using CALD1 Rabbit mAb(1:1000 diluted).Predicted band size:93kDa.Observed band size:70-80kDa.

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  Immunohistochemistry of Caldesmon in paraffin-embedded Human colon cancer tissue using Caldesmon Rabbit mAb at dilution 1/20

Specifications

Product Data

• Clone Name: R05-3D2
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/2000-1/10000
  IHC: 1/20
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Caldesmon
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 93 kDa; Observed MW: 70-80 kDa
• Gene Name: caldesmon 1
• Database Link:
  Entrez Gene 800 Human
  UniProt ID Q05682
• Background: Swiss-Prot Acc.Q05682.Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration .
• Synonyms: CAD; CDM; H-CAD; HCAD; L-CAD; LCAD; MGC21352; NAG22; OTTHUMP00000207949; OTTHUMP00000207954