Calnexin (CANX) Rabbit Monoclonal Antibody [Clone ID: R07-2B1]
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Specifications
| Product Data | |
| Clone Name | R07-2B1 |
| Applications | WB |
| Recommended Dilution | WB: 1/1000 |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide of human Calnexin |
| Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Concentration | lot specific |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Predicted Protein Size | Calculated MW: 68 kDa; Observed MW: 90 kDa |
| Gene Name | calnexin |
| Database Link | |
| Background | Swiss-Prot Acc.P27824.Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.SitesFeature keyPosition(s)Description |
| Synonyms | calnexin; CNX; FLJ26570; IP90; p90 |
| Reference Data | |
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