Caveolin 1 (CAV1) Rabbit Polyclonal Antibody

CAT#: TA383886

Caveolin 1 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded mouse lung, using Caveolin-1 Antibody.

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  Immunofluorescent analysis of A431 cells, using Caveolin-1 Antibody .

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  Western blot analysis of Caveolin-1 expression in A431 cell lysate.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Caveolin-1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 25kDa
• Gene Name: caveolin 1
• Database Link:
  Entrez Gene 857 Human
  UniProt ID Q03135
• Background: Swiss-Prot Acc.Q03135.Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
• Synonyms: BSCL3; CAV; CGL3; MSTP085; VIP21