CD10 (MME) Mouse Monoclonal Antibody [Clone ID: 7C7-1G5-10E3]
Other products for "CD10"
Specifications
Product Data | |
Clone Name | 7C7-1G5-10E3 |
Applications | IHC |
Recommended Dilution | IHC: 1/200 |
Reactivities | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Clonality | Monoclonal |
Immunogen | Synthetic peptide conjugated to KLH. |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Gene Name | membrane metallo-endopeptidase |
Database Link | |
Background | Swiss-Prot Acc.P08473.Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids (PubMed:15283675, PubMed:8168535). Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond (PubMed:17101991). Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9 (PubMed:15283675). Involved in the degradation of atrial natriuretic factor (ANF) (PubMed:2531377, PubMed:2972276). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573). |
Synonyms | atriopeptidase; CALLA; CD10; DKFZp686O16152; Enkephalinase; EPN; MGC126681; MGC126707; NEP; neprilysin |
Reference Data |
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