N Cadherin (CDH2) Rabbit Monoclonal Antibody [Clone ID: R07-4F1]

CAT#: TA383961

N Cadherin Rabbit monoclonal Antibody

Product Images

Western blot detection of N Cadherin in HepG2 cell lysates using N Cadherin Rabbit mAb(1:1000 diluted).Predicted band size:100KDa.Observed band size:140KDa.

Specifications

Product Data

• Clone Name: R07-4F1
• Applications: IP, WB
• Recommended Dilution: WB: 1/1000
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human N Cadherin
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 100 kDa; Observed MW: 140 kDa
• Gene Name: cadherin 2
• Database Link:
  Entrez Gene 1000 Human
  UniProt ID P19022
• Background: Swiss-Prot Acc.P19022.Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density .
• Synonyms: CD325; CDHN; CDw325; N-cadherin; NCAD