Chromogranin A (CHGA) Rabbit Monoclonal Antibody [Clone ID: R04-4J4]

CAT#: TA383997

Chromogranin A Rabbit monoclonal Antibody

Product Images

Western blot detection of Chromogranin A in Rat Brain lysates using Chromogranin A Rabbit mAb(1:1000 diluted).Predicted band size:51kDa.Observed band size:92kDa.

Specifications

Product Data

• Clone Name: R04-4J4
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Chromogranin A
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 51 kDa; Observed MW: 92 kDa
• Gene Name: chromogranin A
• Database Link:
  UniProt ID P10645
• Background: Swiss-Prot Acc.P10645.Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas.CaTatin: Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist (PubMed:15326220). Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa (PubMed:15723172 and PubMed:24723458). Can induce mast cell migration, degranulation and production of cytokines and chemokines (PubMed:21214543). Acts as a potent scavenger of free radicals in vitro (PubMed:24723458). May play a role in the regulation of cardiac function and blood pressure (PubMed:18541522).
• Synonyms: CgA; SP-I