IKK alpha (CHUK) Rabbit Polyclonal Antibody

CAT#: TA384001

IKK alpha/beta Rabbit polyclonal Antibody

Product Images

Western Blot analysis of HepG2 cells using IKKα/β Polyclonal Antibody

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using IKK-alpha/beta Antibody. The picture on the right is blocked with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/100-1/300
  ELISA: 1/20000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human IKK-alpha/beta. AA range:141-190
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):85
• Gene Name: conserved helix-loop-helix ubiquitous kinase
• Database Link:
  Entrez Gene 1147 Human
  UniProt ID O15111
• Background: Swiss-Prot Acc.O15111/O14920.CHUK encodes a member of the serine/threonine protein kinase family. Inhibitor of nuclear factor kappa-B kinase subunit alpha, a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex, phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway, thereby activating the transcription factor.
• Synonyms: IkBKA; IKK-A; IKK-alpha; IKK1; IKKA; NFKBIKA; TCF16