CTNND1 Rabbit Monoclonal Antibody [Clone ID: R01-4G3]

CAT#: TA384060

delta 1 Catenin Rabbit monoclonal Antibody

Product Images

Western blot detection of delta 1 Catenin in C6,3T3,Hela cell lysates using delta 1 Catenin Rabbit mAb(1:1000 diluted).Predicted band size:108kDa.Observed band size:108kDa.

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  Immunohistochemistry of delta 1 Catenin in paraffin-embedded Human colon cancer tissue using delta 1 Catenin Rabbit mAb at dilution 1/50

Specifications

Product Data

• Clone Name: R01-4G3
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20-1/100
  IP: 1/20-1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human delta 1 Catenin
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 108 kDa; Observed MW: 108 kDa
• Gene Name: catenin delta 1
• Database Link:
  Entrez Gene 1500 Human
  UniProt ID O60716
• Background: Swiss-Prot Acc.O60716.Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway . Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
• Synonyms: CAS; CTNND; KIAA0384; p120; p120(cas); p120(ctn); P120CAS; P120CTN