Cytochrome C (CYCS) Rabbit Monoclonal Antibody [Clone ID: R02-9A7]

CAT#: TA384078

Cytochrome C Rabbit monoclonal Antibody

Product Images

Western blot detection of Cytochrome C in K562,Rat Brain,C6,3T3,Hela cell lysates using Cytochrome C Rabbit mAb(1:1000 diluted).Predicted band size:12kDa.Observed band size:14kDa.

Specifications

Product Data

• Clone Name: R02-9A7
• Applications: IF, IP, WB
• Recommended Dilution: WB: 1/1000
  ICC/IF: 1/20-1/50
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Cytochrome C
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 12 kDa; Observed MW: 14 kDa
• Gene Name: cytochrome c, somatic
• Database Link:
  Entrez Gene 54205 Human
  UniProt ID P99999
• Background: Swiss-Prot Acc.P99999.Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.SitesFeature keyPosition(s)Description
• Synonyms: CYC; HCS; OTTHUMP00000202043; OTTHUMP00000202044; THC4