DNAJB6 Rabbit Monoclonal Antibody [Clone ID: R01-8K2]

CAT#: TA384111

DNAJB6 Rabbit monoclonal Antibody


USD 380.00

4 Weeks*

Size
    • 100 ul

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Specifications

Product Data
Clone Name R01-8K2
Applications IHC, WB
Recommended Dilution WB: 1/1000
IHC: 1/20
Reactivities Human, Mouse, Rat
Host Rabbit
Isotype IgG
Clonality Monoclonal
Immunogen Recombinant protein of human DNAJB6
Formulation 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration lot specific
Purification Affinity Purified
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Stability 1 year
Predicted Protein Size Calculated MW: 36 kDa; Observed MW: 36 kDa
Gene Name DnaJ heat shock protein family (Hsp40) member B6
Background Swiss-Prot Acc.O75190.Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.
Synonyms DJ4; DKFZp566D0824; DnaJ; FLJ42837; HHDJ1; HSJ-2; HSJ2; MGC1152; MGC117297; MRJ; MSJ-1; MSJ1
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.