EIF4EBP1 Rabbit Polyclonal Antibody

CAT#: TA384160

4E BP1 Rabbit polyclonal Antibody

Product Images

Western blot detection of 4E-BP1 in SHSY-5Y, C2C12 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

• 

  Immunoprecipitation analysis of Hela cell lysates using 4E-BP1 Rabbit pAb.

• 

  Western blot detection of 4E-BP1 in Jurkat, Hela and C6 cell lysates using 4E-BP1 Rabbit pAb (1:1 diluted). Predicted band size: 13KDa. Observed band size:15~2KDa.

• 

  Western blot detection of 4E-BP1 in C2C12, A549 and 3T3 cell lysates using 4E-BP1 Rabbit pAb (1:1000 diluted). Predicted band size: 13KDa. Observed band size:15~20KDa.

Specifications

Product Data

• Applications: IP, WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 15-20kDa
• Gene Name: eukaryotic translation initiation factor 4E binding protein 1
• Database Link:
  Entrez Gene 1978 Human
  UniProt ID Q13541
• Background: Swiss-Prot Acc.Q13541.4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
• Synonyms: 4E-BP1; 4EBP1; BP-1; MGC4316; PHAS-I