ENSA Rabbit Monoclonal Antibody [Clone ID: R08-1G6]

CAT#: TA384180

ENSA Rabbit monoclonal Antibody

Product Images

Western blot detection of ENSA in Rat Brain,C6,3T3,Hela cell lysates using ENSA Rabbit mAb(1:1000 diluted).Predicted band size:13kDa.Observed band size:15kDa.

Specifications

Product Data

• Clone Name: R08-1G6
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/5000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human ENSA
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 13 kDa; Observed MW: 15 kDa
• Gene Name: endosulfine alpha
• Database Link:
  Entrez Gene 2029 Human
  UniProt ID O43768
• Background: Swiss-Prot Acc.O43768.Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase . Also acts as a stimulator of insulin secretion by interacting with sulfonylurea receptor (ABCC8), thereby preventing sulfonylurea from binding to its receptor and reducing K(ATP) channel currents.
• Synonyms: ARPP-19e; MGC4319; MGC8394; MGC78563