EZH2 Rabbit Polyclonal Antibody

CAT#: TA384195

KMT6 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human tonsil, using KMT6 / EZH2 Antibody.

• 

  Immunofluorescent analysis of Hela cells, using KMT6 / EZH2 Antibody.

• 

  Western blot analysis of KMT6 / EZH2 expression in HEK293 cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/1000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human KMT6 / EZH2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 98kDa
• Gene Name: enhancer of zeste 2 polycomb repressive complex 2 subunit
• Database Link:
  Entrez Gene 2146 Human
  UniProt ID Q15910
• Background: Swiss-Prot Acc.Q15910.Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
• Synonyms: ENX-1; ENX1; EZH1; KMT6; MGC9169