FOXA1 Rabbit Polyclonal Antibody
Other products for "FOXA1"
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommended Dilution | WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human FOXA1 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 49kDa |
Gene Name | forkhead box A1 |
Database Link | |
Background | Swiss-Prot Acc.P55317.Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1. |
Synonyms | HNF-3-alpha; HNF-3A; HNF3A; MGC33105; TCF3A |
Reference Data |
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