FOXA1 Rabbit Polyclonal Antibody

CAT#: TA384247

FOXA1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of FOXA1 expression in HepG2 cell lysate.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human FOXA1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 49kDa
• Gene Name: forkhead box A1
• Database Link:
  Entrez Gene 3169 Human
  UniProt ID P55317
• Background: Swiss-Prot Acc.P55317.Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.
• Synonyms: HNF-3-alpha; HNF-3A; HNF3A; MGC33105; TCF3A