Growth hormone receptor (GHR) Rabbit Polyclonal Antibody

CAT#: TA384300

Growth Hormone Receptor Rabbit polyclonal Antibody

Product Images

Western blot analysis of Growth hormone receptor expression in (1) MCF-7 cell lysate; (2) Mouse brain lysate.

Specifications

Product Data

• Applications: FC, IF, WB
• Recommended Dilution: WB: 1/500-1/2000
  ICC/IF: 1/50-1/200
  FC: 1/100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Growth hormone receptor
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 140kDa
• Gene Name: growth hormone receptor
• Database Link:
  Entrez Gene 2690 Human
  UniProt ID P10912
• Background: Swiss-Prot Acc.P10912.Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
• Synonyms: GHBP