Histone H2A.X (H2AFX) Rabbit Polyclonal Antibody

CAT#: TA384363

Histone H2A.X Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded rat lung, using Histone H2A.X Antibody.

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  Immunofluorescent analysis of Hela cells, using Histone H2A.X Antibody .

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  Western blot analysis of Histone H2A.X expression in Raji cell lysates.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Histone H2A.X
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 14kDa
• Gene Name: H2A histone family member X
• Database Link:
  Entrez Gene 3014 Human
  UniProt ID P16104
• Background: Swiss-Prot Acc.P16104.Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
• Synonyms: H2A.X; H2A/X; H2AX